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Are artificial sweeteners bad for you? WHO, FDA and IARC findings on sucralose, stevia and more.

Updated

What the WHO 2023 guideline on non-sugar sweeteners says, what the FDA allows, how sucralose, saccharin, stevia, monk fruit and sugar alcohols differ, and which catalog products list them.

Quick answer

In May 2023 the WHO issued a conditional recommendation against using non-sugar sweeteners to control body weight or reduce disease risk. Its review found no long-term benefit for body fat and possible links to type 2 diabetes, cardiovascular disease and mortality, which it says may be confounded. It covers sucralose, aspartame, saccharin, acesulfame K, neotame, advantame, cyclamates and stevia, and excludes sugar alcohols. The FDA treats the approved sweeteners as safe within acceptable daily intakes. People with diabetes were outside the WHO guideline.

WHO guideline
May 15, 2023, conditional
Covers
Sucralose, stevia, aspartame and others
Excludes
Sugar alcohols, people with diabetes
FDA view
Safe within acceptable daily intakes

Your avoid list

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01 · A closer look

What the WHO guideline says.

The WHO’s May 2023 guideline recommends against using non-sugar sweeteners (NSS) to control body weight or reduce the risk of noncommunicable diseases. A systematic review found no long-term benefit for reducing body fat in adults or children, and suggested that long-term use may be linked to a higher risk of type 2 diabetes, cardiovascular disease and mortality in adults. The WHO rates the recommendation conditional and says these links may be confounded by participants’ baseline characteristics and complex patterns of use. It does not apply to people with pre-existing diabetes, and the examples it lists are acesulfame K, advantame, aspartame, cyclamates, neotame, saccharin, sucralose and stevia with its derivatives.

WHO: advises not to use non-sugar sweeteners for weight control in newly released guideline (May 15, 2023)

02 · A closer look

What the FDA allows.

The FDA lists six high-intensity sweeteners approved as food additives: aspartame, acesulfame potassium, advantame, neotame, saccharin and sucralose. Steviol glycosides from the stevia leaf and monk fruit extract are on the market through GRAS notices for certain highly purified forms, while whole-leaf and crude stevia extracts are not permitted as sweeteners, and cyclamates are prohibited. Its intake limits are on the aspartame guide linked below. IARC’s official list also places saccharin and its salts in Group 3, not classifiable.

FDA: high-intensity sweeteners (content current as of Dec 19, 2017)

03 · A closer look

Sucralose, stevia, monk fruit and sugar alcohols.

Sucralose is one of the six approved additives, and this checker flags it. Stevia and monk fruit are plant-derived and are not flagged here, though the WHO guideline names stevia derivatives among the sweeteners it advises against for weight control. Sugar alcohols such as erythritol, xylitol, sorbitol and maltitol are not covered by the WHO recommendation. The FDA describes them as sweet at 25 to 100 percent of sugar, slightly lower in calories, not promoting tooth decay and not causing a sudden rise in blood glucose.

Common sweeteners, their regulatory route and how this site treats them
SweetenerLabel namesFDA routeFlagged here
SucraloseSucralose, Splenda, E955Approved food additiveYes
AspartameAspartame, Equal, E951Approved food additiveYes
SaccharinSaccharin, Sweet’N Low, E954Approved food additiveYes
Acesulfame potassiumAcesulfame K, Ace-K, E950Approved food additiveYes
SteviaStevia leaf extract, steviol glycosides, rebaudioside AGRAS notices for purified formsNo
Monk fruitMonk fruit extract, luo han guoGRAS noticesNo
Sugar alcoholsErythritol, xylitol, sorbitol, maltitolDescribed on the FDA sweetener pageNo
FDA: high-intensity sweeteners (content current as of Dec 19, 2017)

04 · A closer look

How to use this on a label.

Read the ingredient list, because “zero sugar”, “diet” and “no added sugar” claims do not say which sweetener is used. The catalog products below include some that list a flagged sweetener and some that list stevia, monk fruit or a sugar alcohol; open a product to see its full label and verification date. Whether to avoid any sweetener is your call. This page is a label reference, not medical advice, and people with diabetes should ask a clinician.

The short answer

Our picks for artificial sweeteners and health

Clear winnerJust Ingredients Chai Protein Powder Stick, 75/100: no tracked additive group on its label, no verified organic claim, verified grass-fed or pasture-raised claim.

No 100 yetNothing on this shelf reaches 100 yet. A 100 needs a label with none of the nine groups we check plus a verified organic claim (and, for animal foods, a verified grass-fed or pasture-raised claim), and none of the 24 labels we have verified here meets all of that. These are the best available picks, not a perfect score.

Runners-upSwerve Allulose Blend (71), Twinings Chai Latte K-Cup Pods (71), and Zevia Fruit Punch (71).

Clear noOptimum Nutrition Coffee Flavored Gold Standard 100% Whey Protein Powder Drink Mix (lists seed oils and artificial sweeteners), Schweppes Diet Ginger Ale (lists artificial sweeteners and artificial preservatives), Pedialyte Grape Electrolyte Powder (lists artificial dyes and artificial sweeteners), plus 10 more with a listed group.

Ranked from 24 of 24 products with current labels. Every product is in the table below; a score reflects labels and claims, not nutrition, allergies or safety.

Compare the recorded labels

Find the ingredients that matter to you.

24 of 24 products

“No …” columns: None found on the label · Listed on the label · Unknown. Diet fit: Fits · Doesn’t fit · Unknown (rules; not medical advice). Claims: verified · not established. Default: most check marks first; not a health score.

Compare product claims and recorded ingredients. Click a column heading to sort.
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75 / 1009 of 9 groups clear · no organic claimFind where to buy ↗Product details →5
71 / 1009 of 9 groups clear · no organic claimFind where to buy ↗Product details →4
71 / 1009 of 9 groups clear · no organic claimFind where to buy ↗Product details →4
71 / 1009 of 9 groups clear · no organic claimFind where to buy ↗Product details →4
71 / 1009 of 9 groups clear · no organic claimBuy on Amazon ↗Product details →4
71 / 1009 of 9 groups clear · no organic claimFind where to buy ↗Product details →4
71 / 1009 of 9 groups clear · no organic claimFind where to buy ↗Product details →4
71 / 1009 of 9 groups clear · no organic claimFind where to buy ↗Product details →4
71 / 1009 of 9 groups clear · no organic claimBuy on Amazon ↗Product details →4
71 / 1009 of 9 groups clear · no organic claimFind where to buy ↗Product details →4
63 / 1008 of 9 groups clear · no organic claimProduct details →3
63 / 1008 of 9 groups clear · no organic claimBuy on Amazon ↗Product details →3
63 / 1008 of 9 groups clear · no organic claimProduct details →3
63 / 1008 of 9 groups clear · no organic claimProduct details →3
63 / 1008 of 9 groups clear · no organic claimFind where to buy ↗Product details →3
63 / 1008 of 9 groups clear · no organic claimProduct details →3
63 / 1008 of 9 groups clear · no organic claimProduct details →3
60 / 1009 of 9 groups clear · no organic claimFind where to buy ↗Product details →4
55 / 1007 of 9 groups clear · no organic claimFind where to buy ↗Product details →3
55 / 1007 of 9 groups clear · no organic claimFind where to buy ↗Product details →2
55 / 1007 of 9 groups clear · no organic claimProduct details →2
55 / 1007 of 9 groups clear · no organic claimProduct details →3
55 / 1007 of 9 groups clear · no organic claimFind where to buy ↗Product details →2
47 / 1007 of 9 groups clear · no organic claimProduct details →2
How the clean score works

No setup needed, and strict: a full 100 needs every additive group clear and a verified organic claim (animal foods also need a verified grass-fed or pasture-raised claim; wild seafood and salt, which have no USDA organic standard, are scored without the organic points, and plant-based milks, cheeses and proteins without the feeding claim). Points: the nine additive groups (seed oils, artificial dyes, MSG, artificial sweeteners, carrageenan, artificial preservatives, hydrogenated oils, corn syrups, banned-abroad additives) share 60 points equally — not found earns a group’s full share, “may contain” earns half, listed earns 0; a verified organic claim is worth 25; a verified grass-fed or pasture-raised claim is worth 15 and counts only for animal foods. No claim, or an expired or unverified claim, earns nothing, so products without those claims cannot reach 100. Unverified or expired ingredient labels receive no score. Equal scores are equal. Ties are ordered by brand. Unknown and stale evidence never passes “Only show matches.” Producer claims and prices do not affect this score. This is not a nutrition, allergy, or safety rating.

As an Amazon Associate I earn from qualifying purchases. Buying links do not influence ingredient results. “Buy on Amazon” opens a reviewed product listing; “Find where to buy” opens the maker’s page. Confirm the package, seller, stock, and current price before checkout. Price observations expire after 30 days.

Primary sources

Sources

  1. WHO: advises not to use non-sugar sweeteners for weight control in newly released guideline (May 15, 2023) who.int
  2. FDA: high-intensity sweeteners (content current as of Dec 19, 2017) fda.gov
  3. FDA: aspartame and other sweeteners in food (current as of Feb 27, 2025) fda.gov
  4. IARC Monographs: agents classified by the IARC Monographs, Volumes 1 to 123 (official list) monographs.iarc.who.int