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Common food preservatives and cancer: what IARC and the FDA actually say.

Updated

A careful, sourced look at the preservatives people ask about: nitrites and processed meat, BHA, potassium bromate, benzoates and TBHQ, what each IARC or regulator classification means, and which catalog products list them.

Quick answer

IARC classifies processed meat as carcinogenic to humans (Group 1) for colorectal cancer, and ingested nitrate or nitrite “under conditions that result in endogenous nitrosation” as probably carcinogenic (Group 2A). BHA and potassium bromate are Group 2B, possibly carcinogenic. An IARC group describes the strength of evidence, not how large the risk is, and sodium benzoate, potassium sorbate and TBHQ are not in those groups.

Processed meat
IARC Group 1 (2015)
Nitrite, nitrosation
Group 2A (2010)
BHA, potassium bromate
Group 2B
Meaning
Evidence strength, not risk size

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01 · A closer look

What IARC groups mean.

IARC classes agents by how strong the evidence is that they can cause cancer: Group 1 carcinogenic, 2A probably, 2B possibly, 3 not classifiable. The group does not say how much risk a normal diet carries, which is why IARC places processed meat and tobacco both in Group 1 despite very different risks.

IARC Monographs: agents classified by the IARC Monographs, Volumes 1 to 123 (official list)

02 · A closer look

Processed meat and nitrite.

In October 2015 IARC (Monographs Volume 114) concluded that eating processed meat, meat transformed by salting, curing, fermentation or smoking, causes colorectal cancer, based on sufficient human evidence, and its press materials say each 50 gram daily portion raised colorectal cancer risk by about 18 percent in the studies reviewed. Nitrite and nitrate are curing agents; IARC’s list classifies “nitrate or nitrite (ingested) under conditions that result in endogenous nitrosation” as Group 2A, probably carcinogenic, from Volume 94 (2010). “Uncured” and “no nitrates added” meats usually use celery juice, a natural nitrate source.

IARC: Q&A on the carcinogenicity of red meat and processed meat (Monographs Volume 114, October 2015)

03 · A closer look

BHA, potassium bromate and the Group 2B label.

IARC’s official list places butylated hydroxyanisole (BHA, evaluated in Volume 40 and Supplement 7, 1987) and potassium bromate (Supplement 7 and Volume 73, 1999) in Group 2B. The list classes butylated hydroxytoluene (BHT) in Group 3, not classifiable. For potassium bromate, the Volume 73 working group had no human data and rated the animal evidence sufficient, with kidney and thyroid tumors in rats, kidney tumors in mice and a marginal kidney tumor increase in hamsters. This site tracks potassium bromate under additives restricted abroad. These ratings do not establish that normal food use causes cancer in people.

IARC Monographs Volume 73: potassium bromate (1999)

04 · A closer look

Benzoates, sorbates and TBHQ.

Sodium benzoate, potassium sorbate, calcium propionate and TBHQ are on our preservatives list because many shoppers avoid synthetic preservatives. They do not appear in the IARC classifications above, so we make no cancer claim about them; regulators permit them within set limits.

05 · A closer look

Products in the catalog.

The products below list at least one flagged preservative on their recorded label, picked across shelves. Open a product to see the ingredient statement and its verification date. Products with no listed preservatives, including many without nitrites, are visible in the comparison tables and the nitrate-free deli meat guide.

The short answer

Our picks for common food preservatives

No pick yetEvery scored common food preservatives label lists at least one of the groups we check, so nothing here earns a pick.

Clear noTakis Fuego Hot Chili Pepper & Lime Tortilla Chips (lists seed oils, artificial dyes, MSG and artificial preservatives), Hillshire Farm Smoked Sausage (lists MSG, artificial preservatives and corn syrups), Crisco All-vegetable Shortening (lists seed oils, artificial preservatives and hydrogenated oils), plus 21 more with a listed group.

Ranked from 24 of 24 products with current labels. Every product is in the table below; a score reflects labels and claims, not nutrition, allergies or safety.

Compare the recorded labels

Find the ingredients that matter to you.

24 of 24 products

“No …” columns: None found on the label · Listed on the label · Unknown. Diet fit: Fits · Doesn’t fit · Unknown (rules; not medical advice). Claims: verified · not established. Default: most check marks first; not a health score.

Compare product claims and recorded ingredients. Click a column heading to sort.
Buy
63 / 1008 of 9 groups clear · no organic claimProduct details →4
63 / 1008 of 9 groups clear · no organic claimProduct details →4
63 / 1008 of 9 groups clear · no organic claimProduct details →4
63 / 1008 of 9 groups clear · no organic claimProduct details →4
55 / 1007 of 9 groups clear · no organic claimFind where to buy ↗Product details →3
55 / 1007 of 9 groups clear · no organic claimProduct details →3
55 / 1007 of 9 groups clear · no organic claimProduct details →3
55 / 1007 of 9 groups clear · no organic claimFind where to buy ↗Product details →4
55 / 1007 of 9 groups clear · no organic claimProduct details →4
55 / 1007 of 9 groups clear · no organic claimProduct details →3
55 / 1007 of 9 groups clear · no organic claimFind where to buy ↗Product details →4
53 / 1008 of 9 groups clear · no organic claimFind where to buy ↗Product details →4
53 / 1008 of 9 groups clear · no organic claimProduct details →4
53 / 1008 of 9 groups clear · no organic claimFind where to buy ↗Product details →4
Bulk foodservice · Canada53 / 1008 of 9 groups clear · no organic claimFind where to buy ↗Product details →4
47 / 1006 of 9 groups clear · no organic claimProduct details →3
47 / 1007 of 9 groups clear · no organic claimProduct details →3
47 / 1006 of 9 groups clear · no organic claimProduct details →3
47 / 1006 of 9 groups clear · no organic claimProduct details →2
47 / 1007 of 9 groups clear · no organic claimFind where to buy ↗Product details →4
47 / 1006 of 9 groups clear · no organic claimProduct details →2
47 / 1007 of 9 groups clear · no organic claimProduct details →4
40 / 1006 of 9 groups clear · no organic claimProduct details →3
39 / 1005 of 9 groups clear · no organic claimProduct details →1
How the clean score works

No setup needed, and strict: a full 100 needs every additive group clear and a verified organic claim (animal foods also need a verified grass-fed or pasture-raised claim; wild seafood and salt, which have no USDA organic standard, are scored without the organic points, and plant-based milks, cheeses and proteins without the feeding claim). Points: the nine additive groups (seed oils, artificial dyes, MSG, artificial sweeteners, carrageenan, artificial preservatives, hydrogenated oils, corn syrups, banned-abroad additives) share 60 points equally — not found earns a group’s full share, “may contain” earns half, listed earns 0; a verified organic claim is worth 25; a verified grass-fed or pasture-raised claim is worth 15 and counts only for animal foods. No claim, or an expired or unverified claim, earns nothing, so products without those claims cannot reach 100. Unverified or expired ingredient labels receive no score. Equal scores are equal. Ties are ordered by brand. Unknown and stale evidence never passes “Only show matches.” Producer claims and prices do not affect this score. This is not a nutrition, allergy, or safety rating.

As an Amazon Associate I earn from qualifying purchases. Buying links do not influence ingredient results. “Buy on Amazon” opens a reviewed product listing; “Find where to buy” opens the maker’s page. Confirm the package, seller, stock, and current price before checkout. Price observations expire after 30 days.

Primary sources

Sources

  1. IARC: Q&A on the carcinogenicity of red meat and processed meat (Monographs Volume 114, October 2015) iarc.who.int
  2. IARC Monographs Volume 94: ingested nitrate and nitrite (2010) publications.iarc.who.int
  3. IARC Monographs Volume 73: potassium bromate (1999) inchem.org
  4. IARC Monographs: agents classified by the IARC Monographs, Volumes 1 to 123 (official list) monographs.iarc.who.int